Antioxidant Activity of Bay (Syzygium polyanthum [Wight] Walp) Leaf Extract Toner
DOI:
https://doi.org/10.59653/jhsmt.v3i03.1853Keywords:
antioxidant, bay leaf, Syzygium polyanthum, tonerAbstract
Facial skin susceptible to oxidative stress due to free radicals can be prevented by increasing the amount of antioxidants. Bay leaf extract is known to have antioxidant activity, it can be formulated into a toner. The purpose of this study was to determine the physical quality and antioxidant activity of bay leaf extract toner. The method used was experimental, with four formulas of variations in the concentration of bay leaf extract addition, namely F0 (0%), F1 (1.5%), F2 (3%), and F3 (6%). The extract was obtained through maceration using 96% ethanol, and then tested for physical quality consisting of organoleptic, pH and viscosity, and antioxidant activity with the DPPH method. The results showed an extract yield of 12.58%. The best formula for bay leaf extract toner preparation was F2, with physical quality including liquid organoleptic, light brown color, the distinctive odor of bay leaf extract; pH 4.74; viscosity 3.81 cP; and IC50 of 46,090 ppm with a very strong antioxidant activity category. Conclusion, bay leaf extract has the potential to be a natural active ingredient in skin care products that is effective in protecting the skin from the effects of free radicals.
Downloads
References
Abdurrahman, N. Z. D., Fitriani, N., & Rusli, R. (2019). Formulasi Sediaan Masker Gel Peel Off Ekstrak Etanol Daun Salam (Syzygium polyanthum) sebagai Antioksidan dengan Metode DPPH. Proceeding of Mulawarman Pharmaceuticals Conferences, 10, 27–31. https://doi.org/10.25026/mpc.v10i1.352
Ahda, A., Setyaningsih, D., Rosalia, R., Aziz, S., Lutfiah, S. L., Apriani, V. D., & Yuniarsih, N. (2022). Aktivitas Antioksidan Dan Formulasi Toner Wajah Berbagai Bahan Aktif Alami: Review Jurnal. Syntax Literate: Jurnal Ilmiah Indonesia, 7(6). https://doi.org/https://doi.org/10.36418/syntax-literate.v7i6.8191
Aizah, S. (2016). Antioksidan Memperlambat Penuaan Dini Sel Manusia. Prosiding Seminar Nasional IV Hayati, 182–185.
Aklimah, M., & Ekayanti, M. (2022). Penetapan Flavonoid Total dan Uji Aktivitas Antioksidan Ekstrak Etanol Daun Cengkeh (Syzygium aromaticum (L). Merr) dan Daun Salam (Syzygium polyanthum Thwaites). Jurnal Kedokteran Universitas Palangka Raya, 10(2). https://doi.org/10.37304/jkupr.v10i2.5536
Andarina, R., & Djauhari, T. (2017). Antioksidan Dalam Dermatologi. Jurnal Kedokteran Dan Kesehatan, 4(1), 39–48. https://doi.org/https://doi.org/10.32539/jkk.v4i1.77
Andiva, H. A., Jamilatun, M., & Lukito, P. I. (2023). Formulasi dan Evaluasi Sabun Cair Kombinasi Ekstrak Kulit Nanas Madu (Ananas comosus (L) Merr .) dan Gel Lidah Buaya (Aloe vera (L) Webb .). Jurnal Jamu Kusuma, 3(1), 35–41.
Apitalau, E. A., Edy, H. J., & Mansauda, K. L. R. (2021). Formulasi dan Uji Efektivitas Antioksidan Sediaan Krim Ekstrak Etanol Daun Salam (Syzygium Polyanthum (Wight) Walpers.) dengan Menggunakan Metode DPPH (1,1-diphenyl-2-picrylhydrazyl). PHARMACON, 10(1). https://doi.org/10.35799/pha.10.2021.32764
Azizah, N., Putriana, N. A., & Tugon, T. D. A. (2024). Formulasi Dan Evaluasi Sediaan Toner Dari Ekstrak Biji Hanjeli (Coix Lacryma-Jobi L.) Sebagai Antioksidan. Majalah Farmasetika, 9(6), 577–595.
Bahriul, P., & Rahman, N. (2014). Uji aktivitas antioksidan ekstrak daun salam (Syzygium polyanthum) dengan menggunakan 1,1-difenil-2- pikrilhidrazil. Jurnal Akademia Kimia, 3(August), 368–374.
Bhadreswara, I. G. R. W., & Susanti, N. M. P. (2023). Potensi Daun Salam (Syzygium polyanthum) Sebagai Antioksidan untuk Menangkal Radikal Bebas. Prosiding Workshop Dan Seminar Nasional Farmasi, 2. https://doi.org/10.24843/wsnf.2022.v02.p49
Chen, H., Xiao, H., & Pang, J. (2020). Parameter optimization and potential bioactivity evaluation of a betulin extract from white birch bark. Plants, 9(3). https://doi.org/10.3390/plants9030392
Haerani, A., Chaerunisa, A., Yohana, & Subarnas, A. (2018). Antioksidan Untuk Kulit. Farmaka, Universitas Padjadjaran, Bandung, 16(2), 135–151.
Herlianto, M. F. J., Hendrawan, S., & Ferdinal, F. (2023). Uji Fitokimia dan Kapasitas Total Antioksidan Ekstrak Daun Salam (Syzygium polyanthum). Jurnal Kesehatan Tambusai, 4(4). https://doi.org/10.31004/jkt.v4i4.16330
Hikmah, N., Yuliet, Y., & Khaerati, K. (2016). Pengaruh Pemberian Ekstrak Daun Salam (Syzygium polyanthum Wight.) terhadap Glibenklamid Dalam Menurunkan Kadar Glukosa Darah Mencit (Mus musculus) yang Diinduksi Aloksan. Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal), 2(1). https://doi.org/10.22487/j24428744.2016.v2.i1.5300
Irianti, T, K., Nuranto, S., & Purwanto. (2021). Antioksidan dan Kesehatan. Gadjah Mada University Press.
Islamiyati, R., & Saputri, I. N. (2018). Uji Perbedaan Aktivitas Antioksidan dengan Variasi Konsentrasi Pelarut Etanol 70% dan 96% pada Ekstrak Etanol Daun Salam Menggunakan Metode Peredaman Radikal Bebas DPPH. Cendekia Journal of Pharmacy, 2(2). https://doi.org/10.31596/cjp.v2i2.28
Jamilatun, M. (2023). Isolation and Phytochemical Testing of Endophytic Fungi from Imperata cylindrica ( L .) Beauv plants . International Journal of Basic and Applied Science, 12(2), 62–71. https://doi.org/https://doi.org/10.35335/ijobas.v12i2.255
Jamilatun, M., Kholisna, M., & Yulianto, S. (2024). Physical Quality and Antifungal Activity of Kalanchoe Pinnata Leaf Extract Ointment against Candida albicans. Quantum Journal of Medical and Health Sciences, 3(5), 18–26.
Jamilatun, M., & Lukito, P. I. (2025). Pendidikan Kesehatan tentang Suplemen Bahan Alam sebagai Pencegah Penyakit Kardiovaskular di Desa Tegalyoso Klaten Selatan. DIMASY: Pengabdian Masyarakat, 2(1), 82–86. https://doi.org/https://doi.org/10.20527/6e8gdf18
Jamilatun, M., Lukito, P. I., & Prasetyo, K. L. (2025). Antioxidant Activity of Mask Combination of Broccoli And Black Glutinous Rice. Quantum Journal of Medical and Health Sciences, 4(1), 52–60.
Jamilatun, M., Lukito, P. I., & Rayhanissa, R. A. D. (2025). Antioxidant Activity of Peel-Off Gel Mask of Aloe Vera and Strawberry. Quantum Journal of Medical and Health Sciences (QJMHS), 4(2), 70–77. https://doi.org/https://doi.org/10.55197/qjmhs.v4i2.154
Jamilatun, M., Lukito, P. I., & Saputri, M. A. (2023). Physical Quality and Sun Protection Factor Value of The Sunscreen Lotion Extract of Carrot ( Daucus carota L .). ULIL ALBAB : Jurnal Ilmiah Multidisiplin, 2(9), 4258–4262. https://doi.org/https://doi.org/10.56799/jim.v2i9.2074
Jamilatun, M., Pratiwi, M. D., & Yulianto, S. (2024). Formulation and Evaluation of Face Mask Gel Peel Off Combination of Avocado Leaf Extract ( Perssea Americana Mill ) and Jicama ( Pachyrrhuzul Erosus L .). 3(8), 1739–1748. https://doi.org/https://doi.org/10.55927/fjst.v3i8.10580
Jamilatun, M., Rahmadianty, H. A., & Lukito, P. I. (2023). Quality Analysis of Cream Scrub Combination of Moringa (Moringa oleifera) Leaf Extract and White Glutinous Rice (Oryza sativa glutinosa) Starch. International Journal of Multidisciplinary Approach Research and Science, 1(03), 302–311. https://doi.org/https://doi.org/10.59653/ijmars.v1i03.167
Jamilatun, M., Rusita, Y. D., & Sari, E. P. (2025). Physical Qualities and Antifungal Activity of Cucumber (Cucumis sativus) Extract Shampoo against Candida albicans. PHARMADEMICA: Jurnal Kefarmasian Dan Gizi, 4(2), 65–74. https://doi.org/https://doi.org/10.54445/pharmademica.v4i2.58
Jamilatun, M., Utami, E. D., & Tolkhah, R. (2025). Antifungal Activity of Hair Dyes Gel from Henna Leaves and Clove Flower. Indonesian Journal of Pharmaceutical (e-Journal), 5(1), 1–11. https://doi.org/10.37311/ijpe.v5i1.27246
Karami, M. R. A. N., Malahayati, S., Hidayah, N., & Budi, S. (2023). Formulasi Dan Uji Stabilitas Sediaan Toner Anti Jerawat Ekstrak Bunga Melati (Jasminum sambac L.). Jurnal Farmasi SYIFA, 1(2), 68–76. https://doi.org/10.63004/jfs.v1i2.235
Kementerian Kesehatan RI. (2023). Farmakope Herbal Indonesia Edisi II Tahun 2017. Pills and the Public Purse.
Makhabbah Jamilatun, Lukito, P. I., Amartya, V. D., Jannah, M., & Dewi, F. A. K. S. (2025). Edukasi Pemanfaatan Bahan Alam Sebagai Bahan Obat Tradisional Di Desa Satriyan Juwiring Klaten. RENATA: Jurnal Pengabdian Masyarakat Kita Semua, 3(2). https://doi.org/https://doi.org/10.61124/1.renata.164
Manríquez, J. J., Cataldo, K., Vera-Kellet, C., & Harz-Fresno, I. (2014). Wrinkles. BMJ Clinical Evidence, 2014(February), 1–47. https://doi.org/10.2307/j.ctt1ffjj0g.28
Mukhlisa, I., Juwita ZR, J. Z. R., & Dita, S. F. (2025). Effectiveness of Chinese Betel Leaf Extract (Peperomia pellucida L) on the Growth of Propionibacterium acnes Bacteria. Journal of Health Science and Medical Therapy, 3(01), 88–101. https://doi.org/10.59653/jhsmt.v3i01.1435
Nazirah, N., Nasution, M. A., Ridwanto, R., & Nasution, H. M. (2023). Skrining fitokimia dan uji aktivitas antioksidan ekstrak metanol daun salam (Syzygium polyanthum (Wight.) Walp.) dari Gampong Bunot, Pidie Jaya dengan metode DPPH. Journal of Pharmaceutical and Sciences. https://doi.org/10.36490/journal-jps.com.v6i5-si.376
Noor, M., Malahayati, S., & Nastiti, K. (2023). Formulasi dan Uji Stabilitas Sediaan Toner Wajah Ekstrak Buah Pare (Momordica charantia L) sebagai Anti Jerawat dengan Variasi Surfaktan. Jurnal Riset Kefarmasian Indonesia, 5(1). https://doi.org/10.33759/jrki.v5i1.330
Prakoeswa, F. R. S., & Sari, W. A. (2022). Penuaan Kulit dan Terapi yang Aman Bagi Geriatri: Artikel Review. Jurnal Sains Dan Kesehatan, 4(5). https://doi.org/10.25026/jsk.v4i5.1294
Putri, R., Farmasi, G. P., Tinggi, S., Kesehatan, I., & Belas, T. (2020). LOTION ANTIOKSIDAN EKSTRAK DAUN SALAM (Syzygium polyanthum Wight Walp.). Jurnal Kesehatan Tujuh Belas, 2(1).
Rahayu, E. S., Salfiyadi, T., & Reca, R. (2024). Effectiveness of Gargling with Lemon Juice (Citrus lemon) and Betel Leaf Decoction on Debris Index and Saliva pH of Elementary School Students in Aceh Besar District. Journal of Health Science and Medical Therapy, 2(03 SE-Articles), 249–258. https://doi.org/10.59653/jhsmt.v2i03.1139
Suleman, A. W., Wahyuningsih, S., Puspitasari, Y., & Jangga. (2023). Formulasi Sediaan Serum Antioksidan Ekstrak Etanol Daun Salam (Syzygium Polyanthum) Menggunakan Metode Radikal Bebas Dpph. Pharmamedica Journal, 8(2).
Tambunan, P. M., Nadia, S., & Siregar, F. A. Z. (2024). Skrining dan Uji Aktivitas Antioksidan Ekstrak Etanol Daun Salam (Syzygium polyanthum (Wight) Walp) dengan Metode FRAP (Ferric Reducing Antioxidant Power). Forte Journal, 4(1), 66–72. https://doi.org/10.51771/fj.v4i1.702
Wahyuni, A., Purwanjani, W., An, U., & Purwodadi, N. (2024). Uji Aktivitas Anti Aging Sediaan Gel Ekstrak Etanol 70 % Daun Salam ( Syzygium polyanthum ). 3(1), 39–60.
Wahyuni, W., Saputri, R. K., & Hutahaen, T. A. (2023). Uji Antioksidan Dan Efektivitas Sediaan Toner Ekstrak Daun Binahong Merah (Anredera cordifolia). Indonesian Journal of Health Science, 3(2a). https://doi.org/10.54957/ijhs.v3i2a.591
Winarsih, H. (2017). Antioksidan Alami & Radikal Bebas Potensi dan Aplikasinya dalam Kesehatan. Yogyakarta: Kanisius.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Makhabbah Jamilatun, Pradea Indah Lukito, Melda Aulia Zahra

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-ShareAlike that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).