WBC and RBC Indicators among People with Hepatitis and Kidney Failure
DOI:
https://doi.org/10.59653/ijmars.v3i02.1525Keywords:
Hepatitis, CRP, HCV, WBC, hematologyAbstract
The global pandemic of HBV and HCV infections produces liver insufficiency. This study examines blood markers in renal failure patients with and without viral hepatitis. The study included 90 blood samples from chronic renal failure patients (67 males and 23 females) undergoing hemodialysis (HD) in the unit. (HCV) and (HBV) were detected in patients' serum by ELISA, while WBC, RBC, lymphocyte, and neutrophil counts were measured using an automated hematology analyzer. This study assessed 90 CRF patients (67 men, 23 women). 22 men and 14 women (40%) had HBV and HCV; 60% (45 men and 9 women) did not. The HCV patient count was 20, and the HBV was 16. The average CRF patient had normal WBC levels (5.29.109/L). RBC counts were 3.25 x 1012/L in 64.44% of 58/90 patients, 26 with hepatitis virus, below the typical range of 3.5–5.5. The mean neutrophil count was 70.13 % higher than 50–70, and 59/90 (65.55%). 22 patients had hepatitis, with the highest value being 82. Within the normal 20-40 range, the lymphocyte % mean was 20.99. No significant difference (p>0.05).
Downloads
References
82 Chronic Hepatitis-C Infection and Kidney Failure. (2023). American Journal of Kidney Diseases, 81(4). https://doi.org/10.1053/j.ajkd.2023.01.084
Abdelnour, G. E., Matar, G. M., Sharara, H. M., & Abdelnoor, A. M. (1997). Detection of anti-hepatitis C-virus antibodies and hepatitis C-virus RNA in Lebanese hemodialysis patients. European Journal of Epidemiology, 13(8). https://doi.org/10.1023/A:1007468322940
Alavian, S. M., Adibi, P., & Zali, M. R. (2005). Hepatitis C virus in Iran: Epidemiology of an emerging infection. In Archives of Iranian Medicine (Vol. 8, Issue 2).
Bagheri, S., Fard, G. B., Talkhi, N., Zadeh, D. R., Mobarra, N., Mousavinezhad, S., Khamse, F. M., & Bafghi, H. (2024). Laboratory Biochemical and Hematological Parameters: Early Predictive Biomarkers for Diagnosing Hepatitis C Virus Infection. Journal of Clinical Laboratory Analysis, 38(24), e25127. https://doi.org/10.1002/jcla.25127
Bukhari, K. T., & Zafar, H. (2013). Blood complete picture examination; a surrogate test for screening hepatitis c viral infection. Asian Journal of Agriculture and Biology, 1(2).
Conrad, M. E., Schwartz, F. D., & Young, A. A. (1964). Infectious hepatitis-A generalized disease. A study of renal, gastrointestinal and hematologic abnormalities. The American Journal of Medicine, 37(5). https://doi.org/10.1016/0002-9343(64)90027-0
Dong, R., Luo, Z., Xue, H., Shao, J., Chen, L., Jin, W., Yang, L., Shen, C., Xu, M., Wu, M., & Wang, J. (2025). Development and Validation of an Explainable Machine Learning Model for Warning of Hepatitis E Virus‐Related Acute Liver Failure. Liver International, 45(6), e70129. https://doi.org/10.1111/liv.70129
Entedhar R. Sarhat, , Nawal A. Al- Madani, & Nazar. A. Naji. (2023). Evaluation of Serum Paraoxonase and Lipid Profile in Patients with Chronic Renal Failure Pre and post Hemodialysis. Tikrit Journal of Pure Science, 22(2). https://doi.org/10.25130/tjps.v22i2.628
Fabrizi, F., & Messa, P. (2018). Managing hepatitis C therapy failures and chronic kidney disease. In Expert Review of Clinical Pharmacology (Vol. 11, Issue 11). https://doi.org/10.1080/17512433.2018.1534202
Fujiwara, A., Sakaguchi, K., Fujioka, S., Iwasaki, Y., Senoh, T., Nishimura, M., Terao, M., & Shiratori, Y. (2008). Fibrosis progression rates between chronic hepatitis B and C patients with elevated alanine aminotransferase levels. Journal of Gastroenterology, 43(6). https://doi.org/10.1007/s00535-008-2183-8
Goldman, L., & Schafer, A. I. (2012). Goldman’s Cecil Medicine: Twenty Fourth Edition. In Goldman’s Cecil Medicine: Twenty Fourth Edition (Vols. 1–2). https://doi.org/10.1016/C2009-0-42832-0
Locatelli, F., Vecchio, L. Del, & Pozzoni, P. (2002). The importance of early detection of chronic kidney disease. Nephrology Dialysis Transplantation, 17(SUPPL. 11). https://doi.org/10.1093/ndt/17.suppl_11.2
Marks, P. W. (2013). Hematologic Manifestations of Liver Disease. Seminars in Hematology, 50(3). https://doi.org/10.1053/j.seminhematol.2013.06.003
Muhsun, L. H., Ch, M. B., Al-Akayshi, R. J., Mhawes, A. A., Hikmet, L., Ch, M. M. B., Ragad, J., Al-Akayshi, C. A. B. M., Abed, A., & Ch, M. M. B. (2015). Evaluation Study of Patients Infected with Chronic Hepatitis C in Iraq. Al-Kindy College Medical Journal, 1111(22).
Parlak, E. (2019). Management of hepatitis C patients with kidney failure. Ortadoğu Tıp Dergisi, 11(4). https://doi.org/10.21601/ortadogutipdergisi.479176
Qirbi, N., & Hall, A. J. (2001). Epidemiology of hepatitis B virus infection in the Middle East. In Eastern Mediterranean health journal = La revue de santé de la Méditerranée orientale = al-Majallah al-ihhīyah li-sharq al-mutawassi (Vol. 7, Issue 6). https://doi.org/10.26719/2001.7.6.1034
Shankar, A., Klein, R., & Klein, B. E. K. (2006). The association among smoking, heavy drinking, and chronic kidney disease. American Journal of Epidemiology, 164(3). https://doi.org/10.1093/aje/kwj173
Weiner, I. D., & Wingo, C. S. (1997). Hypokalemia--consequences, causes, and correction. Journal of the American Society of Nephrology, 8(7). https://journals.lww.com/jasn/fulltext/1997/07000/hypokalemia_-consequences,_causes,_and_correction_.17.aspx
Xiang, Y., Li, R., Cai, J., & Jiang, Q. (2024). Three Artificial Liver Models of Treatment of Acute-on-Chronic Liver Failure. Therapeutics and Clinical Risk Management, 20(0), 731–740. https://doi.org/10.2147/tcrm.s485620
Zhang, Q. L., & Rothenbacher, D. (2008). Prevalence of chronic kidney disease in population-based studies: Systematic review. BMC Public Health, 8. https://doi.org/10.1186/1471-2458-8-117
Downloads
Published
How to Cite
Issue
Section
Categories
License
Copyright (c) 2025 Nora S. A. Aljaff, Shaymaa Jaber Hameed, Ohood Abdullah Ibrahim
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-ShareAlike that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
